Testo E300

Testosterone esters are less extreme than free testosterone. Testosterone Enanthate should be taken at two to four week intervals. This is because when injected intramuscularly, testosterone esters in oils are absorbed gradually from the lipid phase. 98% of testosterone in plasma is bound to a specific testosterone estradiol binding globulin, with the remaining 2% being free.

The amount of this sex-hormone binding globulin (SHBG) in the plasma will generally determine the distribution of testosterone between free and bound forms and the free testosterone concentration will determine its half-life. About 90% of the taken dose of testosterone is metabolised and excreted as glucuronic and sulphuric acid combinations of testosterone and its metabolites in urine. About 6% of a dose is excreted as unconjugated forms in the feces. The liver is the primary location in which inactivation of testosterone occurs. Testosterone is metabolized to various 17-keto steroids through two different pathways.

Reports about the half-life of testosterone in literature has been found to vary from 10 to 100 minutes. Testosterone enanthate injections, USP is suggested in conditions associated with a deficiency or absence of endogenous testosterone, as a replacement therapy. In addition, these injections are also reported to be successful for Idiopathic gonadotropin or luteinizing hormone-releasing hormone (LHRH) deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation women with advancing inoperable metastatic (skeletal) mammary cancer who are one to five years postmenopausal. This therapy is widely used for women who require ablation of the ovaries, though it comes with a higher risk of developing breast cancer.

Side effects include gynecomastia, difficulty in urination due to prostate hyperplasia, hypertension due to water retention, fatigue caused by continuous use, vomiting, nausea, prolonged erection, swelling of the extremities, yellowness in the eyes.